Breast Cancer
Melnikov AA, Scholtens DM, Wiley EL, Khan SA, Levenson VV.
Array-based multiplex analysis of DNA methylation in breast cancer tissues.
J Mol Diagn. 2008 Jan;10(1):93-101.
Pasquali L, Bedeir A, Ringquist S, Styche A, Bhargava R, Trucco G.
Quantification of CpG island methylation in progressive breast lesions from normal to invasive carcinoma.
Cancer Lett. 2007;257(1):136-44.
Hoque MO, Feng Q, Toure P, Dem A, Critchlow CW, Hawes SE, Wood T, Jeronimo C, Rosenbaum E, Stern J, Yu M, Trink B, Kiviat NB, Sidransky D.
Detection of aberrant methylation of four genes in plasma DNA for the detection of breast cancer.
J Clin Oncol. 2006;24(26):4262-9.
Li S, Rong M, Iacopetta B.
DNA hypermethylation in breast cancer and its association with clinicopathological features.
Cancer Lett. 2006;237(2):272-80.
Additional Publications
Fackler MJ, Malone K, Zhang Z, Schilling E, Garrett-Mayer E, Swift-Scanlan T, Lange J, Nayar R, Davidson NE, Khan SA, Sukumar S.
Quantitative multiplex methylation-specific PCR analysis doubles detection of tumor cells in breast ductal fluid.
Clin Cancer Res. 2006 Jun 1;12(11 Pt 1):3306-10.
Shinozaki M, Hoon DS, Giuliano AE, Hansen NM, Wang HJ, Turner R, Taback B.
Distinct hypermethylation profile of primary breast cancer is associated with sentinel lymph node metastasis.
Clin Cancer Res. 2005 Mar 15;11(6):2156-62.
Bae YK, Brown A, Garrett E, Bornman D, Fackler MJ, Sukumar S, Herman JG, Gabrielson E.
Hypermethylation in histologically distinct classes of breast cancer.
Clin Cancer Res. 2004;10(18 Pt 1):5998-6005.
Dulaimi E, Hillinck J, Ibanez de Caceres I, Al-Saleem T, Cairns P.
Tumor suppressor gene promoter hypermethylation in serum of breast cancer patients.
Clin Cancer Res. 2004;10(18 Pt 1):6189-93.
Veeck J, Niederacher D, An H, Klopocki E, Wiesmann F, Betz B, Galm O, Camara O, Durst M, Kristiansen G, Huszka C, Knuchel R, Dahl E.
Aberrant methylation of the Wnt antagonist SFRP1 in breast cancer is associated with unfavourable prognosis.
Oncogene. 2006;25(24):3479-88. Epub 2006 Jan 30.
Giacinti L, Claudio PP, Lopez M, Giordano A.
Epigenetic information and estrogen receptor alpha expression in breast cancer.
Oncologist. 2006;11(1):1-8. Review.
Umetani N, Mori T, Koyanagi K, Shinozaki M, Kim J, Giuliano AE, Hoon DS.
Aberrant hypermethylation of ID4 gene promoter region increases risk of lymph node metastasis in T1 breast cancer.
Oncogene. 2005;24(29):4721-7.
Hu M, Yao J, Cai L, Bachman KE, van den Brule F, Velculescu V, Polyak K
Distinct epigenetic changes in the stromal cells of breast cancers.
Nat Genet. 2005;37(8):899-905.
Li S, Rong M, Iacopetta B.
DNA hypermethylation in breast cancer and its association with clinicopathological features.
Cancer Lett. 2005 Jul 16; [Epub ahead of print]
Yeo W, Wong WL, Wong N, Law BK, Tse GM, Zhong S
High frequency of promoter hypermethylation of RASSF1A in tumorous and non-tumourous tissue of breast cancer.
Pathology. 2005;37(2):125-30.
Alvarez S, Diaz-Uriarte R, Osorio A, Barroso A, Melchor L, Paz MF, Honrado E, Rodriguez R, Urioste
M, Valle L, Diez O, Cigudosa JC, Dopazo J, Esteller M, Benitez J.
A predictor based on the somatic genomic changes of the BRCA1/BRCA2 breast cancer tumors identifies the non-BRCA1/BRCA2 tumors with BRCA1 promoter hypermethylation.
Clin Cancer Res. 2005;11(3):1146-53.
Leitch AM, Minna JD, Euhus DM. Lewis CM, Cler LR, Bu DW, Zochbauer-Muller S, Milchgrub S, Naftalis EZ,
Promoter hypermethylation in benign breast epithelium in relation to predicted breast cancer risk.
Cancer Res. 2005;11(1):166-72.
Martens JW, Nimmrich I, Koenig T, Look MP, Harbeck N, Model F, Kluth A, Bolt-de Vries J, Sieuwerts AM, Portengen H, Meijer-Van Gelder ME, Piepenbrock C, Olek A, Hofler H, Kiechle M, Klijn JG, Schmitt M, Maier S, Foekens JA.
Association of DNA methylation of phosphoserine aminotransferase with response to endocrine therapy in patients with recurrent breast cancer.
Cancer Res. 2005;65(10):4101-17.
Mehrotra J, Ganpat MM, Kanaan Y, Fackler MJ, McVeigh M, Lahti-Domenici J, Polyak K, Argani P, Naab T, Garrett E, Parmigiani G, Broome C, Sukumar S.
Estrogen receptor/progesterone receptor-negative breast cancers of young African-American women have a higher frequency of methylation of multiple genes than those of Caucasian women.
Clin Cancer Res. 2004;10(6):2052-7.
Khan S, Kumagai T, Vora J, Bose N, Sehgal I, Koeffler PH, Bose S.
PTEN promoter is methylated in a proportion of invasive breast cancers.
Int J Cancer. 2004;112(3):407-10.
Lee A, Kim Y, Han K, Kang CS, Jeon HM, Shim SI.
Detection of Tumor Markers Including Carcinoembryonic Antigen, APC, and Cyclin D2 in Fine-Needle Aspiration Fluid of Breast.
Arch Pathol Lab Med. 2004;128(11):1251-1256.
Szyf M, Pakneshan P, Rabbani SA.
DNA methylation and breast cancer.
Biochem Pharmacol. 2004;68(6):1187-97. Review.
Muller HM, Widschwendter A, Fiegl H, Ivarsson L, Goebel G, Perkmann E, Marth C, Widschwendter M.
DNA methylation in serum of breast cancer patients: an independent prognostic marker.
Cancer Res 2003;15(63):7641-5
Evron E; Dooley WC; Umbricht CB; Rosenthal D; Sacchi N; Gabrielson E; Soito AB; Hung DT; Ljung B; Davidson NE; Sukumar S.
Detection of breast cancer cells in ductal lavage fluid by methylation-specific PCR.
Lancet 2001;357(9265):1335-6
Yang X, Yan L, Davidson NE.
DNA methylation in breast cancer.
Endocrine-Related Cancer 2001;8:115-27
Esteller, M., Silva, J.M., Dominguez, G, Bonilla, F., Matias-Guiu, X., Lerma, E., Bussaglia, E., Prat, J., Harkes, IC, Repasky, EA, Gabrielson, E, Schutte, M, Baylin, SB, Herman, JG.
Promoter hypermethylation and BRCA1 inactivation in sporadic breast and ovarian tumors.
J Natl Cancer Inst. 2000; 92(7): 564-9.
Conway K, McConnell B, Bowring C, Donald C, Warren S, Vertino P.
TMSI, a novel proapoptotic caspase recruitment domain protein, is a target of methylation-induced gene silencing in human breast cancers.
Cancer Res. 2000;60:6236-42.