Esophageal Cancer
Kuester D, Dar AA, Moskaluk CC, Krueger S, Meyer F, Hartig R, Stolte M, Malfertheiner P, Lippert H, Roessner A, El-Rifai W, Schneider-Stock R.
Early involvement of death-associated protein kinase promoter hypermethylation in the carcinogenesis of Barrett's esophageal adenocarcinoma and its association with clinical progression.
Neoplasia. 2007;9(3):236-45.
Wu DL, Sui FY, Jiang XM, Jiang XH.
Methylation in esophageal carcinogenesis.
World J Gastroenterol. 2006;12(43):6933-40. Review.
Guo M, House MG, Akiyama Y, Qi Y, Capagna D, Harmon J, Baylin SB, Brock MV, Herman JG.
Hypermethylation of the GATA gene family in esophageal cancer.
Int J Cancer. 2006;119(9):2078-83.
Guo M, Ren J, House MG, Qi Y, Brock MV, Herman JG.
Accumulation of promoter methylation suggests epigenetic progression in squamous cell carcinoma of the esophagus.
Clin Cancer Res. 2006;12(15):4515-22.
Additional Publications
Sato F, Meltzer SJ.
CpG island hypermethylation in progression of esophageal and gastric cancer.
Cancer. 2006;106(3):483-93. Review.
Brock MV, Gou M, Akiyama Y, Muller A, Wu TT, Montgomery E, Deasel M, Germonpre P, Rubinson L, Heitmiller RF, Yang SC, Forastiere AA, Baylin SB, Herman JG.
Prognostic importance of promoter hypermethylation of multiple genes in esophageal adenocarcinoma.
Clin Cancer Res. 2003;9(8):2912-9.
Schulmann K, Sterian A, Berki A, Yin J, Sato F, Xu Y, Olaru A, Wang S, Mori Y, Deacu E, Hamilton J, Kan T, Krasna MJ, Beer DG, Pepe MS, Abraham JM, Feng Z, Schmiegel W, Greenwald BD, Meltzer SJ.
Inactivation of p16, RUNX3, and HPP1 occurs early in Barrett's-associated neoplastic progression and predicts progression risk.
Oncogene. 2005;24(25):4138-48.
Zou H, Molina JR, Harrington JJ, Osborn NK, Klatt KK, Romero Y, Burgart LJ, Ahlquist DA.
Aberrant methylation of secreted frizzled-related protein genes in esophageal adenocarcinoma and Barrett's esophagus.
Int J Cancer. 2005;116(4):584-91.
Darnton SJ, Hardie LJ, Muc RS, Wild CP, Casson AG
Tissue inhibitor of metalloproteinase-3 (TIMP-3) gene is methylated in the development of esophageal adenocarcinoma: loss of expression correlates with poor prognosis.
Int J Cancer. 2005;115(3):351-8.
Yamashita K, Upadhyay S, Osada M, Hoque MO, Xiao Y, Mori M, Sato F, Meltzer SJ, and Sidransky D.
Pharmacologic unmasking of epigenetically silenced tumor suppressor genes in esophageal squamous cell carcinoma.
Cancer Cell 2002;2:485-95.